@article{6855, keywords = {Adolescent, Adult, Age Factors, Child, Child, Preschool, Female, Humans, India, Infant, leprosy, Male, Pregnancy, Recurrence, Retrospective Studies, Sex Factors, Urban Health}, author = {Saha S P and Das K K}, title = {Study of the characteristics and causes of relapse amongst leprosy cases in an urban area (Calcutta).}, abstract = {

In this retrospective study of the 3737 cases of leprosy released from treatment and followed-up during 1975 to 1990, 63 had relapsed giving an overall relapse rate of 1.69%. The relapse rate was significantly higher in the immunologically unstable N?L (Borderline) cases (2.9%). It was also higher in those who had dapsone monotherapy (1.92%) compared to those who had multidrug therapy (1.01%). The relapse rate was higher in the 10 to 29 years age group and among those who became pregnant suggesting puberty and pregnancy could be risk factors. Males had a significantly higher relapse rate (2.1%) than females (1.1%). 45.2% of relapses in N (Non-lepromatous) cases occurred within 24 months and 71.4% within 36 months of stopping treatment. In those having monotherapy, 57.1% of relapses occurred within 24 months and 76.8% within 36 months. Regularity in treatment did not seem to have much influence on relapse rates.

}, year = {1992}, journal = {Indian journal of leprosy}, volume = {64}, pages = {169-78}, month = {1992 Apr-Jun}, issn = {0254-9395}, language = {eng}, }