@article{6756,
  keywords = {Adult, Aged, Gallium Radioisotopes, Humans, Leishmaniasis, Cutaneous, Leishmaniasis, Mucocutaneous, leprosy, Radionuclide Imaging},
  author = {Braga F J and Abreu C M and Abreu P R and Camargo E E and Rivitti M C and Tedesco-Marchesi L C and Gambini D J and Barritault L},
  title = {[2 infectious granulomatous diseases (leprosy and cutaneous and mucous leishmaniasis) by scintigraphic methods].},
  abstract = {<p>Leprosy is a multiform chronic infectious granulomatous disease caused by Mycobacterium leprae, that affects over 12 million people in the world. Cutaneous and mucous leishmaniasis (CML) is also a chronic granulomatous infectious disease, caused by Leishmania brasiliensis and transmitted to man by the mosquitoes of the Phlebotominae family. It is a worldwide spread disease. We studied one case of Borderline-wirchowian leprosy and 2 cases of CML with Gallium-67 (GA-67) scintigraphy. Ga-67 is a radiopharmaceutical known for its property of concentrating in inflammatory sites. In the leprosy patient, Ga-67 accumulated in the skin in a moderate, homogeneous and disseminated way (outlined skin); in the area of the face, the uptake was important and homogeneous (image in beard). Several internal organs accumulated Ga-67. As for the 2 CML patients, Ga-67 accumulated focally, in different degrees, in the affected anatomical areas. The leprosy patient was not under treatment and the 2 CML were under treatment (20 and 40 days, respectively). In the 3 cases, all affected areas accumulated Ga-67. Intensity differences of uptake may be explained both by different degrees of inflammatory processes (between leprosy and CML) and by treatment lasting. It is possible that Ga-67 scintigraphy may be useful for the evaluation of these 2 diseases extent and also for the therapy follow-up.</p>},
  year = {1992},
  journal = {Bulletin de la Societe de pathologie exotique (1990)},
  volume = {85},
  pages = {53-6},
  month = {1992},
  issn = {0037-9085},
  language = {fre},
}