@article{6755, keywords = {Animals, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, Humans, Immunoblotting, Immunodiffusion, leprosy, Liver, Phosphatidylcholines, Rabbits, Rats}, author = {Deshpande R G and Khan M B and Navalkar R G}, title = {Immunoreactivity of a mammalian liver component with leprosy sera.}, abstract = {
Sera from 77 leprosy patients in various stages of infection--tuberculoid (TT), lepromatous (LL), borderline tuberculoid and borderline lepromatous--15 contacts and 21 normal healthy individuals, were assayed in an indirect enzyme-linked immunosorbent assay and dot enzyme immunoassay using ethanol-soluble and thermostable extract of liver as the antigen. The highest incidences of reaction were found in untreated LL patients (100%) and in TT patients (91%), while the sera from borderline patients showed a comparatively lower incidence (43%). Some of the sera from contacts of leprosy patients (6/15) also showed high reactivity. Assays using lecithin as an antigen did not exhibit any reaction.
}, year = {1992}, journal = {International archives of allergy and immunology}, volume = {97}, pages = {345-9}, month = {1992}, issn = {1018-2438}, doi = {10.1159/000236143}, language = {eng}, }