@article{6616,
  keywords = {Antibodies, Bacterial, Enzyme-Linked Immunosorbent Assay, Female, Humans, leprosy, Male, Mycobacterium leprae, Saliva, Sensitivity and Specificity},
  author = {Iushin IM and Diachina M N and Bochanovskiĭ V A and Iushchenko A A},
  title = {[Detection of antibodies to M. leprae in saliva of lepric patients].},
  abstract = {<p>Saliva of 116 lepric patients were scanned for antibodies in ELISA (with M. leprae cultivated in vitro used as antigen) in order to work out an invasion-free diagnostic tool for lepra. The ELISA findings for "saliva-serum" pairs from same patients showed an increased level of antibodies both in serum and saliva in 39.7% of cases, and matching of results (positive and negative ones) was observed in 73.3% of patients. The increasing level of specific antibodies as observed in intensification of the lepric process in blood serum occurred simultaneously with its increase in saliva. The invasion-free diagnostics of lepra is promising for examinations of contact persons and of population in endemic regions as well as for evaluating the efficiency of the antilepric therapy.</p>},
  year = {2005},
  journal = {Klinicheskaia laboratornaia diagnostika},
  pages = {52-4},
  month = {2005 Jan},
  issn = {0869-2084},
  language = {rus},
}