@article{6198,
  keywords = {Animals, Axons, Demyelinating Autoimmune Diseases, CNS, Dystroglycans, Dystrophin-Associated Protein Complex, Humans, leprosy, Mice, Mycobacterium leprae, Myelin Sheath, Schwann Cells},
  author = {Rambukkana A},
  title = {Mycobacterium leprae-induced demyelination: a model for early nerve degeneration.},
  abstract = {<p>The molecular events that occur at the early phase of many demyelinating neurodegenerative diseases are unknown. A recent demonstration of rapid demyelination and axonal injury induced by Mycobacterium leprae provides a model for elucidating the molecular events of early nerve degeneration which might be common to neurodegenerative diseases of both infectious origin and unknown etiology. The identification of the M. leprae-targeted Schwann cell receptor, dystroglycan, and its associated molecules in myelination, demyelination and axonal functions suggests a role for these molecules in early nerve degeneration.</p>},
  year = {2004},
  journal = {Current opinion in immunology},
  volume = {16},
  pages = {511-8},
  month = {2004 Aug},
  issn = {0952-7915},
  doi = {10.1016/j.coi.2004.05.021},
  language = {eng},
}