@article{6153,
  keywords = {Agglutination Tests, Antibodies, Bacterial, Antigens, Bacterial, Glycolipids, Humans, Latex, leprosy, Microspheres, Mycobacterium leprae, Sensitivity and Specificity},
  author = {Vaishnavi C and Agnihotri N and Kumar B and Kaur S and Ganguly N K},
  title = {Field utility of phenolic glycolipid coated latex agglutination test for rapid detection of bacilliferous leprosy cases.},
  abstract = {<p>Serum samples were collected from eighty-three leprosy patients and twenty-five healthy controls supposedly not exposed to Mycobacterium leprae infection. Phenolic glycolipid-1 coated latex agglutination test (PGL-LAT) was carried out with the serum samples to detect antibodies specific to M. leprae. Samples showing positive agglutination were 50% in the lepromatous leprosy (LL) group showing no erythema nodosum leprosum (ENL) complications, 66.6% in LL group with ENL complication, 60% in borderline lepromatous (BL) group, 50% in borderline (BB) and 33.3% in borderline tuberculoid (BT). The patients belonging to the tuberculoid (TT) group and most of the long-term treated patients were interestingly negative, and so were sera from all the healthy controls. PGL-LAT developed by us therefore is specific and a fairly sensitive technique to detect antibodies specific to M. leprae and will be very useful in field conditions.</p>},
  year = {1992},
  journal = {Journal of hygiene, epidemiology, microbiology, and immunology},
  volume = {36},
  pages = {169-73},
  month = {1992},
  issn = {0022-1732},
  language = {eng},
}