@article{5526, keywords = {Adolescent, Adult, C-Reactive Protein, Erythema Nodosum, Female, Humans, Leprosy, Borderline, Leprosy, lepromatous, Male, Middle Aged, Predictive Value of Tests, Reaction Time, Remission Induction, Alpha 1-Antitrypsin}, author = {Sehgal V N and Bhattacharya S N and Shah Y and Sharma V K and Gupta C K}, title = {Reaction in leprosy: acute phase reactant response during and after remission.}, abstract = {
Sera from 25 patients with type 1 (Lepra), upgrading and downgrading, and type 2 (erythema nodosum leprosum [ENL]) reactions were assayed, during the reaction and after its clinical remission, for changes in levels of alpha-1-antitrypsin (A1A) and C-reactive protein (CRP). The results were compared with those from normal healthy adults and patients of leprosy without history and/or clinical evidence of reaction. The A1A levels correlated better with changes in status of type 1 reaction; whereas CRP levels correlated well with alterations in type 2 reactions and were definitely superior to A1A in this situation for monitoring the course of these episodes.
}, year = {1992}, journal = {International journal of dermatology}, volume = {31}, pages = {632-4}, month = {1992 Sep}, issn = {0011-9059}, doi = {10.1111/j.1365-4362.1992.tb03981.x}, language = {eng}, }