@article{3579, keywords = {Animals, Disease Models, Animal, Female, leprosy, Liver, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mycobacterium leprae, Spleen}, author = {Gangadharam P R and Dhople A M}, title = {Utility of beige mouse in leprosy research.}, abstract = {
Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.
}, year = {1992}, journal = {Indian journal of leprosy}, volume = {64}, pages = {475-81}, month = {1992 Oct-Dec}, issn = {0254-9395}, language = {eng}, }