@article{3381, keywords = {Dapsone, Drug Resistance, Bacterial, Drug Resistance, Multiple, Drug Therapy, Combination, Humans, Leprostatic Agents, leprosy, Male, Middle Aged, Rifampin}, author = {Norman G and Joseph G and Ebenezer G and Rao SP and Job CK}, title = {Secondary rifampin resistance following multi-drug therapy--a case report.}, abstract = {

This is the first report of secondary resistance to rifampin following MDT in a patient with prolonged, but irregular treatment. Repeated mouse foot-pad studies demonstrated resistance to dapsone after several years of monotherapy, and following subsequent MDT the studies demonstrated the development of resistance to rifampin.

}, year = {2003}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {71}, pages = {18-21}, month = {2003 Mar}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v71n1a04.pdf}, language = {eng}, }