@article{33127,
  author = {Trianita MN and Rumondor BB and Prakoeswa AC and Iswahyudi I and Adriaty D and Kusumaputra B and Listiawan MY and Agusni I and Izumi S and Duthie M},
  title = {A simpler diagnostic method using blood collection on filter paper to determine anti-natural octyl disaccharide-leprosy infectious disease research institute diagnostic in household contacts of leprosy patients},
  abstract = {<p>The high prevalence among children shows continued transmission from adult and lack of disease control by the health system. Detection of anti-NDO-LID-1 has been known to be more effective to predict the development of leprosy in household contacts than just detecting PGL-1 or LID- 1 alone. However, serodiagnosis is not available in poorer-settings area and the procedure (venepuncture) is still inconvenient to some people. These problems can be solved by using finger-prick blood sample on filter paper. This study aims to prove the effectiveness of using capillary blood samples on filter paper to detect the positivity of Ig G antibody against NDO-LID-1 antigen in asymptomatic household contacts. Seventeen samples of capillary blood on filter paper and sera were tested for IgG anti-NDO-LID-1 using ELISA. There was no significant difference between IgG level from filter paper and serum (p=0.754) and there was also a strong positive correlation (R=0.906) between the two procedures. These findings show that the use of filter paper and NDO-LID-1 is worthy of further investigations, especially for those with lower bacillary load or contacts of leprosy patients.</p>
},
  year = {2019},
  journal = {Dermatology Reports},
  volume = {11},
  issn = {2036-7392},
  url = {https://www.pagepress.org/journals/index.php/dr/article/view/8048},
  doi = {10.4081/dr.2019.8048},
  language = {eng},
}