@article{3292,
  keywords = {Adult, Humans, leprosy, Male, Prednisone, Rifampin, Severity of Illness Index},
  author = {Jih M and Kimyai-Asadi A and Levis W},
  title = {Reversal reaction to Hansen's disease.},
  abstract = {<p>A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented. His clinical features included erythematous, edematous plaques and peripheral neuropathy. Reversal reactions are caused immunologically by enhanced cell-mediated (Th-1) immunity to Mycobacterium leprae, resulting in inflammation of infected tissues, such as skin and nerves. Acute neuritis can lead to permanent nerve damage and necessitate prompt treatment with prednisone and/or clofazamine.</p>},
  year = {2002},
  journal = {Journal of drugs in dermatology : JDD},
  volume = {1},
  pages = {70-1},
  month = {2002 Jul},
  issn = {1545-9616},
  language = {eng},
}