@article{327, keywords = {China, Clofazimine, Dapsone, Drug Therapy, Combination, Follow-Up Studies, Humans, leprosy, Recurrence, Retrospective Studies, Rifampin, Risk Factors}, author = {Li H Y}, title = {Problems of leprosy relapse in China.}, abstract = {

The proportion of relapses among all patients detected each year increased steadily since the initiation of the national leprosy control program in China with dapsone monotherapy in 1955, reaching 18%-24% in the more leprosy-endemic provinces along the coast. Relapses were also reported in the formerly rifampin-plus-dapsone-treated patients. So far, only three paucibacillary relapses after 6 months of multidrug therapy (MDT) have been reported, and these were due to misclassification at the time of diagnosis. A short course of MDT should be given to all formerly dapsone- and/or rifampin-plus-dapsone-cured patients for the prevention of relapse. If not, they should be screened every 1 to 2 years for any possible signs of relapse, and MDT given when needed.

}, year = {1993}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {61}, pages = {1-7}, month = {1993 Mar}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v61n1a01.pdf}, language = {eng}, }