@article{32378,
  author = {Pawar M and Singh M},
  title = {Sparfloxacin-induced photo-onycholysis and photosensitivity characteristically sparing lepromatous skin lesions: an interesting observation.},
  abstract = {<p>Sparfloxacin is an antibiotic in the quinolone group of antibacterial agents, which often induce photosensitive skin reactions, more often phototoxic reactions than photoallergic ones, and sometimes associated photo-onycholysis. We present a case of phototoxic dermatitis with photo-onycholysis in a 38-year-old man probably induced by sparfloxacin, which was prescribed to him along with rifampicin and clofazimine because he was suffering from borderline lepromatous leprosy. He developed exaggerated sunburn-like eruptions mainly on sun-exposed sites along with painful onycholysis of the fingernails. Interestingly, the hypopigmented patches of leprosy were spared, which is a very rare phenomenon. Withdrawal of sparfloxacin along with administration of systemic steroids and other supportive measures helped heal the skin eruptions with hyperpigmentation, but the photo-onycholysis was slow to resolve.</p>
},
  year = {2018},
  journal = {Acta dermatovenerologica Alpina, Pannonica, et Adriatica},
  volume = {27},
  pages = {149-151},
  issn = {1581-2979},
  url = {https://s3-eu-west-1.amazonaws.com/thejournalhub/10.15570/actaapa.2018.30/actaapa.2018.30.pdf},
  language = {eng},
}