@article{32097,
  keywords = {leprosy, Burden, Histomorphological spectrum, Clinicopathological correlation, Hansens, H & E stain, Fite Faraco stain, India},
  author = {Firdous F and Sridevi P and Majeed A and Kirit R and Abeddin MA},
  title = {To assess the burden of and trends of Hansens disease - Mainly by assessing the histomorphological spectrum and clinicopathological correlation, at a tertiary care hospital in Telangana State, India.},
  abstract = {<p><strong>Context: </strong>Leprosy an important public health problem which needs to be addressed. <strong>Aims: </strong>We study the histopathological features of leprosy in skin biopsies and categorize them into various types based on microscopic features. Clinico pathological correlation was done in all cases. <strong>Materials and Methods: </strong>Skin biopsies after adequate fixation in 10% of formalin, were routinely processed and paraffin embedded sections of 5 μ thickness were stained with H and E and fite -faraco stain and were studied microscopically. <strong>Results: </strong>A total of 1200 skin biopsies were obtained from patients of skin department during a period of two years from May 2016 to May 2018,out of which 136 cases were clinically diagnosed as Hansens and among them 116 were confirmed as Hansens histologically . Among them - Lepromatous leprosy 61 cases,- Borderline lepromatous leprosy 18 cases, Tuberculoid leprosy-11 cases, Borderline tuberculoid leprosy- 19 cases and lepra reaction[ENL]-7 cases, rest 20 cases included indeterminate leprosy and other d/ds. With an age range of 11 -68 years, majority were in 2nd decade, with male to female ratio of 2.5:1. LL was the most common type of leprosy (%). Majority of biopsies were of multibacillary type (52.5%). Clinicopathological correlation was observed in all cases. <strong>Conclusions: </strong>For diagnosis, correlation of clinical and histopathological features along with special stain [fite faraco] appears to be more useful than considering any of the single parameters alone.</p>
},
  year = {2018},
  journal = {World journal of pharmaceutical and medical research},
  volume = {4},
  pages = {148-154},
  url = {https://tinyurl.com/yaamatce},
  language = {eng},
}