@article{31572,
  keywords = {leprosy, Total IgG total, IgG anti PGL-I, Duration of therapy, Reaction of leprosy, multibaciller},
  author = {Retnowati E and Wijaya H and Agusni I},
  title = {Total igG and Ig anti PGL-I with duration of the therapy and reactions in multibaciller leprosy},
  abstract = {<p>Leprosy is still a main health problem. Leprosy is characterized by various clinical manifestations and variations between clinical spectra which depend on host immune response. Humoral immune response in leprosy has been studied by examining the immunoglobulin (Ig) level. The purpose of this study is to know the correlation of total IgG and IgG anti PGL-I with duration of therapy and reaction of leprosy in multibaciller leprosy patients.. This study was conducted from June to December 2013 using the samples from multibaciller leprosy patients in the District of Sampang-Madura. The sera were examined for Total IgG with radial immunodiffusion (RID) method and IgG anti PGL-I with enzyme linked immunosorbent assay (ELISA). The data were collected and analyzed for correlation test. The median of total IgG was 172 IU/mL and the median of IgG anti PGL-I was 574.33 U/mL. The median of total IgG in patients with less than three months therapy was lower than the patients who received more than and as equal as three months treatment. The median of total IgG in patients with reaction was higher in reactive than non reactive. The median of IgG anti PGL-I level in patients receiving therapy less than three months was higher than more than or equal as three months groups. The median of IgG anti PGL-I in patients with reaction was higher than in patients with no reaction. There was no significant correlation between total IgG and IgG anti PGL-I with duration of therapy and reaction of leprosy. There was no significant correlation between total IgG and IgG anti PGL-I with duration of therapy and reaction of leprosy.</p>
},
  year = {2016},
  journal = {Indonesian journal of clinical pathology and medical laboratory },
  volume = {22},
  pages = {268–273},
  url = {https://tinyurl.com/ybng8d9j},
  language = {eng, ind},
}