@article{3140,
  keywords = {Adult, Female, Humans, Immunity, leprosy, Male},
  author = {Flies E L and Bachmann A E and C Sasiain M and Ruibal Ares B},
  title = {[Immunological examination of patients with undetermined leprosy].},
  abstract = {<p>The immunological competence of eleven patients with undetermined leprosy was compared with that of ten normal volunteers of the same age and sex distribution; these controls have not had previous contact with leprosy. The following parameters were studied in peripheral blood cells: 1) percentage of lymphocyte bearing surface immunoglobulins, as revealed by immunofluorescence; 2) percentage of lymphocyte bearing complement receptors, as studied by antibody and complement coated erithrocyte rosetting; 3) percentage of T cells, as revealed by spontaneous sheep erithrocyte rosettes; 4) blastogenic and mytogenic response of cultured lymphocytes to PHA and 5) cell migration inhibition test using lepromine (80 x 10(6) bacilli/ml) as antigen. Skin reactions to lepromine were also assayed. In the six lepromine-positive patients with undetermined leprosy, no major immunological alterations could be detected. On the contrary, the five lepromine-negative patients showed important alterations which could well be considered as precursors of lepromatous leprosy.</p>},
  year = {1975},
  journal = {Revista de la Asociacion Argentina de Microbiologia},
  volume = {7},
  pages = {81-5},
  month = {1975 Sep-Dec},
  issn = {0325-1713},
  language = {spa},
}