@article{3098,
  keywords = {Belgium, Clofazimine, Drug Administration Schedule, Drug Therapy, Combination, Follow-Up Studies, Humans, Leprostatic Agents, leprosy, Ofloxacin, Recurrence, Rifampin},
  author = {Pattyn S and Grillone S},
  title = {Relapse rates and a 10-year follow-up of a 6-week quadruple drug regimen for multibacillary leprosy.},
  abstract = {<p>Between 1989 and 1993, 136 multibacillary leprosy patients received a 6-week treatment regimen consisting of daily rifampicin 600 mg, ofloxacin 400 mg, clofazimine 100 mg and a weekly dose of 100 mg minocycline. A previous analysis after a mean follow-up of 4-7 years revealed a relapse rate of 2%, involving six late (after more than 5 years of follow-up) relapses. During the following years, 12 more relapses appeared during years 8-9 of follow-up. A mean follow-up period of 5 years is insufficient to evaluate treatment regimens in multibacillary leprosy. The present regimen cannot be recommended.</p>},
  year = {2002},
  journal = {Leprosy review},
  volume = {73},
  pages = {245-7},
  month = {2002 Sep},
  issn = {0305-7518},
  url = {https://leprosyreview.org/article/73/3/24-5247},
  doi = {10.47276/lr.73.3.245},
  language = {eng},
}