@article{30725, keywords = {leprosy, Mast Cells, Metachromatic, Lepromatous, Tuberculoid}, author = {Jindal S and Manjari M and Girdhar M}, title = {Role of mast cells in leprosy- A study of 62 cases.}, abstract = {
BACKGROUND
Mast cells have received little attention in leprosy, but evidence linking them with delayed-type hypersensitivity reactions raises the possibility that they may be of some importance in leprosy.
MATERIALS AND METHODS
The present study is a descriptive study. Biopsies obtained from the clinically diagnosed patients were fixed in 10% formalin, processed and three sections of 6 µm thickness were cut and stained with routine Haematoxylin and Eosin (Culling, Allison, Barr 1985), by Toluidine Blue and by Modified Thionin/Acridine Orange method.
RESULTS
Mean number of mast cells were more in lepromatous leprosy than in tuberculoid.
CONCLUSION
This study reflects the variety of immunological reactions occurring in leprosy and the role of mast cells in these immunological phenomena.
}, year = {2017}, journal = {Journal of evolution of medical and dental sciences}, volume = {6}, pages = {5328-5331}, issn = {22784748}, url = {https://www.jemds.com/data_pdf/shivani%20jindal-%20--sept%2018-.pdf}, doi = {10.14260/jemds10.14260/Jemds/2017/1157}, language = {eng}, }