@article{30494,
  keywords = {Mycobacterium leprae, leprosy, Cutaneous vasculitis},
  author = {Diallo M and Diack N D and Diatta B A and Ndiaye A and Dieng M T},
  title = {Necrotizing Vasculitis Due to a Severe Type II Leprosy Reaction},
  abstract = {<p><strong>Introduction:</strong> Despite the wide spectrum of the clinical manifestations of leprosy, necrotizing cutaneous vasculitis has rarely been reported as a manifestation of this disease. We report a case of cutaneous vasculitis due to a type II leprosy reaction, secondary to lepromatous leprosy. <strong>Case report:</strong> A 38-years-old Gambian man was admitted for necrotic and infiltrated purpura of acral distribution (limbs, ears and nose), which was associated with multiple subcutaneous inflammatory nodules, epistaxis, polyarthralgia, fever and a poor general health status. Mycobacterium Leprae was isolated from the nasal mucosa (bacillary index 3 +) and the biopsy of the purpuric lesions revealed a leukocytoclastic vasculitis. A multidrug therapy concurrently with oral corticosteroids was started with good clinical results after 4 weeks. <strong>Discussion:</strong> Cutaneous necrotizing vasculitis has been described as a rare manifestation of eryhtema nodosum leprosum in medical literature. We think, in endemic areas, erythema nodosum leprosum can be added to the list of the possible etiologies of cutaneous vasculitis.</p>
},
  year = {2017},
  journal = {International journal of advances in medical sciences},
  volume = {2},
  pages = {1-3},
  url = {http://ijams.kibanresearchpublications.com/index.php/IJAMS/article/download/11/9},
  language = {eng},
}