BACKGROUND: Non-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers.
AIM: The objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease.
DESIGN: A prospective study.
SETTING: An institution-based clinic.
PARTICIPANTS: Seven treated patients with Hansen's disease, with a mean age of 38.33 years, with nine non-healing trophic ulcer of more than 6 weeks duration.
MEASUREMENTS: Photographs were taken before treatment and at every subsequent sitting. Area and volume were calculated at baseline and every subsequent sitting till the closure was achieved.
MATERIALS AND METHODS: The healthy ulcers were treated with PRFM at weekly intervals, repeated once a week for a maximum of five sittings as per requirement.
RESULTS: The mean percentage improvement in the area was 93.52%, and volume was 97.74% at the end of the second sitting. All ulcers closed by a maximum of five sittings. No adverse events were noted.
CONCLUSION: PRFM for the treatment of trophic ulcers in treated patients with Hansen's disease is a feasible, safe, simple and inexpensive method.
}, year = {2017}, journal = {Journal of cutaneous and aesthetic surgery}, volume = {10}, pages = {3-7}, issn = {0974-2077}, url = {http://www.jcasonline.com/article.asp?issn=0974-2077;year=2017;volume=10;issue=1;spage=3;epage=7;aulast=Nagaraju}, doi = {10.4103/JCAS.JCAS_17_16}, language = {eng}, }