@article{32009, keywords = {leprosy, Guillain{\textendash}Barr{\'e} syndrome, Borderline tuberculoid leprosy, Type 1 lepra reaction, Neuropathy}, author = {Dash D and Saluja A and Singh R and Bhatia R and Tripathi M}, title = {Guillain{\textendash}Barre syndrome: A rare presentation of borderline tuberculoid leprosy with Type 1 lepra reaction}, abstract = {
Guillain{\textendash}Barre syndrome (GBS) is an autoimmune polyradiculoneuropathy usually preceded by respiratory tract or gastrointestinal infection. The pathogenesis in GBS is based on molecular mimicry mechanism. Hansen{\textquoteright}s disease is common in India and is the most common infectious cause of neuropathy. We describe a 42-year-old man who was being treated for borderline tuberculoid leprosy and developed Type 1 lepra reaction followed by GBS and responded to plasmapheresis. Lepra reaction may lead to exposure of neural antigens, resulting in autoimmune mechanism and demyelination of peripheral nerves.
}, year = {2018}, journal = {Journal of neurosciences in rural practice}, volume = {9}, pages = {423-425}, issn = {0976-3147}, url = {https://tinyurl.com/ydxb8n4o}, doi = {10.4103/jnrp.jnrp_510_17}, language = {eng}, }