@phdthesis{29326,
  keywords = {Amyotrophic Lateral Sclerosis (ALS), leprosy},
  author = {El Idrissi B},
  title = {Complement in neuroinflammation : Studies in leprosy and Amyotrophic Lateral Sclerosis},
  abstract = {<p>The complement system is a part of the innate immunity, and plays an important role in host immunity and inflammation. We previously identified the terminal membrane attack complex (MAC) of the complement system as a key determinant of neurodegeneration and demonstrated that its inhibition is neuroprotective. Besides being part of a mechanism of defence to invading pathogens, MAC has the capacity to cause damage to self-cells and is consequently implicated in many diseases.</p>
},
  year = {2017},
  journal = {Faculty of Medicine (AMC-UvA)},
  pages = {275 p.},
  publisher = {University of Amsterdam},
  address = {Amsterdam},
  url = {http://hdl.handle.net/11245.1/6455df2c-f9a6-403a-8061-7260d7446e3b},
  language = {eng},
}