@article{28682, keywords = {Trichuris, Trichuriasis, Soil, Sensitivity and Specificity, Sample Size, Prevalence, Population Surveillance, Organizational Case Studies, Kenya, Humans, Hookworm Infections, Helminths, Elephantiasis, Filarial, Data Collection, Cost-Benefit Analysis, Child, Preschool, Child, Ascaris lumbricoides, Ascariasis, Animals, Ancylostomatoidea, Age Factors, Adolescent}, author = {Smith JL and Sturrock H and Assefa L and Nikolay B and Njenga S and Kihara J and Mwandawiro C and Brooker S}, title = {Factors associated with the performance and cost-effectiveness of using lymphatic filariasis transmission assessment surveys for monitoring soil-transmitted helminths: a case study in Kenya.}, abstract = {
Transmission assessment surveys (TAS) for lymphatic filariasis have been proposed as a platform to assess the impact of mass drug administration (MDA) on soil-transmitted helminths (STHs). This study used computer simulation and field data from pre- and post-MDA settings across Kenya to evaluate the performance and cost-effectiveness of the TAS design for STH assessment compared with alternative survey designs. Variations in the TAS design and different sample sizes and diagnostic methods were also evaluated. The district-level TAS design correctly classified more districts compared with standard STH designs in pre-MDA settings. Aggregating districts into larger evaluation units in a TAS design decreased performance, whereas age group sampled and sample size had minimal impact. The low diagnostic sensitivity of Kato-Katz and mini-FLOTAC methods was found to increase misclassification. We recommend using a district-level TAS among children 8-10 years of age to assess STH but suggest that key consideration is given to evaluation unit size.
}, year = {2015}, journal = {The American journal of tropical medicine and hygiene}, volume = {92}, pages = {342-53}, issn = {1476-1645}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347340/pdf/tropmed-92-342.pdf}, doi = {10.4269/ajtmh.14-0435}, language = {eng}, }