@article{27843,
  author = {Coelho de Sousa V and Laureano A and Cardoso J},
  title = {Wade histoid leprosy revisited.},
  abstract = {<p>An 18-year-old man presented with a 4-year history of erythematous patches on the trunk, followed 2-years later by multiple nodules, mostly located on the limbs, and distal paresthesias. Two close contacts were treated for leprosy during his childhood. Histopathological examination revealed a histiocytic infiltrate with acid-fast bacilli on Ziehl-Neelsen stain. The slit-skin and nasal smears showed numerous acid-fast bacilli. The correlation between clinical, epidemiological, histopathological, and microbiological features allowed the diagnosis of lepromatous leprosy, histoid variant. Multidrug therapy as recommended by the WHO was initiated. A rapid and sustained improvement was seen. Histoid leprosy is a rare manifestation of lepromatous leprosy, first described by Wade in 1960. Since then few cases have been reported, the majority of them from countries with a high prevalence of the disease. Early recognition and treatment are of most importance to prevent neurological disabilities and achieve epidemiological control.</p>
},
  year = {2016},
  journal = {Dermatology online journal},
  volume = {22},
  issn = {1087-2108},
  url = {http://escholarship.org/uc/item/5d78t619#page-4},
  language = {eng},
}