@article{27404, keywords = {Zero leprosy transmission, Transmission, Strategy, leprosy}, author = {Smith WC and Aerts A and Kita E and Virmond M}, title = {Time to define leprosy elimination as zero leprosy transmission?}, abstract = {
In 1982, in response to growing evidence of resistance to the antibacterial drug, dapsone, WHO recommended that all patients with leprosy be treated with a short-course combination of three antibacterial drugs, rifampicin, dapsone, and clofazimine.1 This multidrug therapy reduced the number of patients with leprosy being treated from 5{\textperiodcentered}3 million in 1985 to 3{\textperiodcentered}1 million in 1991.2 The reduction in prevalence inspired the World Health Assembly in 1991 to set a target to eliminate leprosy as a public health problem by 2000, defining elimination as a global prevalence rate below one case per 10 000 of the population.
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}, year = {2016}, journal = {The Lancet. Infectious diseases}, volume = {16}, issn = {14733099}, url = {http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(16)00087-6/fulltext}, doi = {10.1016/S1473-3099(16)00087-6}, }