@article{273,
  keywords = {Adult, China, Drug Therapy, Combination, Female, Humans, Leprostatic Agents, Leprosy, Borderline, Leprosy, lepromatous, Leprosy, Tuberculoid, Male, Prevalence, Retrospective Studies, Severity of Illness Index, Surveys and Questionnaires},
  author = {Shen J and Liu M and Zhou M and Wengzhong L},
  title = {Occurrence and management of leprosy reaction in China in 2005.},
  abstract = {<p><b>BACKGROUND: </b>Leprosy reactions are a major cause of disability before, during and after anti-bacterial treatment. Prompt diagnosis and correct management of reaction is a crucial matter for improving the quality of leprosy health services.</p><p><b>OBJECTIVES: </b>To describe the pattern of leprosy reaction and its management in China during 2005.</p><p><b>METHODS: </b>A retrospective survey using a questionnaire was carried out in all the provinces of China at the beginning of 2006. Patients included were those presenting with leprosy reaction between 1 January and 31 December 2005.</p><p><b>RESULTS: </b>452 questionnaires from 25 provinces were analysed. There were 313 male and 139 female patients who had 159 Type I reactions, 273 Type II reactions and 20 Type I and II mixed reaction. 72.4% of reactions occurred in the first year of MDT and 27.6% of patients during the second year of MDT. The highest frequency of reaction was during the first 6 months of MDT; 57.3% of patients developed new nerve impairment during and after MDT.</p><p><b>CONCLUSIONS: </b>New nerve function impairment and disability still occurs among patients during and after MDT. The early detection and management of leprosy reaction remains important.</p>},
  year = {2009},
  journal = {Leprosy review},
  volume = {80},
  pages = {164-9},
  month = {2009 Jun},
  issn = {0305-7518},
  url = {https://leprosyreview.org/article/80/2/16-4169},
  language = {eng},
}