@article{25759,
  keywords = {Sweet Syndrome, Reactions, Pathogenesis, Mimicry, leprosy, Erythema Nodosum},
  author = {Mahajan V and Abhinav C and Mehta K and Chauhan S},
  title = {Erythema nodosum leprosum mimicking Sweet’s syndrome: an uncommon presentation},
  abstract = {<div dir="ltr">Erythema nodosum leprosum (ENL) lesions may uncommonly develop ulceration, necrosis, pustulation or bullae. This 60year-old female was hospitalised with previously undiagnosed multibacillary (BL) leprosy and Sweet’s syndrome-like ENL, a presentation that is rarely reported. In addition to skin lesions simulating Sweet’s syndrome, she had anaemia, elevated ESR, and a peripheral leucocytosis with neutrophilia, the laboratory features of Sweet’s syndrome. The final diagnosis was made from chronic iridocyclitis, presence of lepra bacilli in slit-skin smears, and histology. The pathogenesis of Sweet’s-like ENL remains conjectural. In Sweet’s syndrome a complex interplay of various cytokines leading to an abundance of pro-inflammatory cytokines in the target tissues has been postulated to initiate an abnormal tissue response to certain antigens; such findings may eventually explain these uncommon lepra reactions as well.</div>
},
  year = {2014},
  journal = {Leprosy review},
  volume = {85},
  pages = {322-327},
  url = {https://leprosyreview.org/article/85/4/32-2327},
  language = {eng},
}