@article{23917,
  keywords = {Amino Acid Sequence, Antitubercular Agents, Bacterial Proteins, Cell Division, Cytoskeletal Proteins, Gene Expression Regulation, Bacterial, Humans, Molecular Sequence Data, Mycobacterium, Mycobacterium tuberculosis, Sequence Homology, Amino Acid, Tuberculosis},
  author = {Hong W and Deng W and Xie J},
  title = {The structure, function, and regulation of Mycobacterium FtsZ.},
  abstract = {<p>FtsZ is a widely distributed major cytoskeletal protein involved in the archaea and bacteria cell division. It is the most critical component in the division machinery and similar to tubulin in structure and function. Four major roles of FtsZ have been characterized: cell elongation, GTPase, cell division, and bacterial cytoskeleton. FtsZ subunits can be assembled into protofilaments. Mycobacteria consist of a large family of medical and environmental important bacteria, such as M. leprae, M. tuberculosis, the pathogen of leprosy, and tuberculosis. Structure, function, and regulation of mycobacteria FtsZ are summarized here, together with the implication of FtsZ as potential novel drug target for anti-tuberculosis therapeutics.</p>},
  year = {2013},
  journal = {Cell biochemistry and biophysics},
  volume = {65},
  pages = {97-105},
  month = {2013 Mar},
  issn = {1559-0283},
  doi = {10.1007/s12013-012-9415-5},
  language = {eng},
}