@article{23899, keywords = {Female, Fumarate Hydratase, Genetic Predisposition to Disease, Humans, Leiomyomatosis, Middle Aged, Neoplastic Syndromes, Hereditary, Pedigree, Skin Neoplasms, Uterine Neoplasms}, author = {Mandal RK and Koley S and Banerjee S and Kabiraj SP and Ghosh SK and Kumar P}, title = {Familial leiomyomatosis cutis affecting nine family members in two successive generations including four cases of Reed's syndrome.}, abstract = {

Reed's syndrome or familial leiomyomatosis cutis et uteri is an autosomal dominant disorder, characterized by multiple cutaneous and uterine leiomyomas. We report here a case of a 53-year-old woman who presented to us with multiple painful nodules over different parts of her body. Based on the histopathological examination, imaging, and past medical records, a diagnosis of Reed's syndrome was made. Three of her sisters had similar disease. Subsequently, it was found that a total of nine members of their family in two successive generations were affected with cutaneous leiomyomas. The present case series has been reported for its interesting clinical presentations and rarity.

}, year = {2013}, journal = {Indian journal of dermatology, venereology and leprology}, volume = {79}, pages = {83-7}, month = {2013 Jan-Feb}, issn = {0973-3922}, doi = {10.4103/0378-6323.104674}, language = {eng}, }