@article{23748,
  keywords = {Pain mechanisms, leprosy, Hemicrania continua, Central sensitization},
  author = {Ferreira K S and Freitas D J and Speciali J G},
  title = {Is there a relation between Hemicrania continua and Leprosy?},
  abstract = {The association of hemicrania continua and leprosy has been described in 2008. This relation can be causal or casual. Hemicrania continua is a strictly unilateral, moderate to severe, continuous, indomethacin-responsive primary headache with autonomic cranial symptoms and leprosy is an usual cause of peripheral neuropathy. Prevalence has fallen in the past years, but transmission continues and leprosy remains a public health problem. The objective of this study is to report one case of headache fulfilling the IHS criteria for HC, presented during the course of leprosy. A 61 years old woman started hypo and hiperpigmented lesions with impaired sensation to touch on right side of face (malar). She had biopsy in facial lesion and histopathology compatible with a borderline leprosy form. At the same time, she reported new headaches, daily and continuous, without pain-free periods, unilateral (which were located in the same side of the leprosy lesion in face), throbbing and severe (VAS = 8) with ipsilateral conjuntival injection and lacrimation that improved with indomethacin. We hypothesize that the local injury on the face of this patient predisposes a mechanism of central sensitization, resulting in trigeminal autonomic cephalgia. Relation between trigemino-autonomic cephalalgias and leprosy provides insights into craniofacial pain mechanisms.},
  year = {2012},
  journal = {Indian journal of leprosy},
  volume = {84},
  pages = {317-20},
  url = {http://ijl.org.in/oct-dec-2012/7%20KS%20Ferreira%20(317-320).pdf},
  language = {eng},
}