@article{23266,
  keywords = {Protein oxidation, Protein carbonyl, leprosy, Antioxidant vitamins},
  author = {Asalkar A and Girish S and Naoley R},
  title = {Protein oxidation and antioxidant vitimins in leprosy},
  abstract = {<p>Aims The presence of carbonyl groups in proteins has been used as a marker of ROS-mediated protein oxidation. The present work was undertaken to study the importance of endogenous antioxidants like Vitamin C and vitamin E in different types of leprosy patients. Methods: Total 30 leprosy cases were studied. Patients were subjected to various tests like, serum protein carbonyl as an index of protein oxidation, while serum Vitamin C and Vitamin E levels as endogenous antioxidants. Results: An increased level of protein carbonyl indicates oxidative stress .The levels of Vitamins C, E decreased significantly in leprosy. Conclusions: Protein carbonyl can be used as sensitive indicator of oxidative stress in leprosy patients. Vitamin C and vitamin E can be supplemented along with anti-leprosy drugs to control the protein oxidation in leprosy patients.</p>
},
  year = {2011},
  journal = {International Journal of Pharmaceutical Sciences and Research},
  volume = {2},
  pages = {2870-73},
  month = {10/2011},
  url = {http://ijpsr.com/bft-article/protein-oxidation-and-antioxidant-vitamins-in-leprosy/},
  language = {eng},
}