@article{22243, keywords = {Adolescent, Adult, Aged, Aged, 80 and over, C-Reactive Protein, Case-Control Studies, Female, Humans, Interferon-gamma, leprosy, Male, Middle Aged, Periodontal Diseases, Stomatognathic Diseases, Young Adult}, author = {Motta ACF and Furini RB and Simão JCL and Vieira MB and Ferreira MAN and Komesu MC and Foss N}, title = {Could leprosy reaction episodes be exacerbated by oral infections?}, abstract = {
INTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection.
METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after elimination of the foci of infection.
RESULTS: Group I presented more reactions than group II did, and improvement of the reactions after dental treatment. Serum CRP and IP-10 did not differ before and after the dental treatment, but differed between the groups.
CONCLUSIONS: Oral infection could be an exacerbating factor in leprosy reactions.
}, year = {2011}, journal = {Revista da Sociedade Brasileira de Medicina Tropical}, volume = {44}, pages = {633-5}, month = {2011 Oct}, publisher = {Scielo}, address = {Rio De Janeiro}, issn = {1678-9849}, url = {http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822011000500022&nrm=iso}, doi = {10.1590/s0037-86822011000500022}, language = {eng}, }