@article{22203,
  keywords = {Africa, Western, Animals, Antibodies, Bacterial, Antigens, Bacterial, Ape Diseases, Biomarkers, Diagnosis, Differential, Glycolipids, leprosy, Mycobacterium leprae, Pan troglodytes, polymerase chain reaction, Polymorphism, Single Nucleotide, Zoonoses},
  author = {Ishii N and Udono T and Fujisawa M and Idani G and Tanigawa K and Miyamura T and Suzuki K},
  title = {[Leprosy in a chimpanzee].},
  abstract = {<p>Leprosy is suspected to develop after a long period of latency following infection with Mycobacterium leprae (M. leprae) during infancy, but definitive proof has been lacking. We found a rare case of leprosy in a chimpanzee (Pan troglodytes) born in West Africa (Sierra Leone) and brought to Japan around 2 years of age. At 31, the ape started exhibiting pathognomic signs of leprosy. Pathological diagnosis, skin smear, serum anti-phenolic glycolipid-I (PGL-I) antibody, and by PCR analysis demonstrated lepromatous leprosy. Single-nucleotide polymorphism (SNP) analysis verified the West African origin of the bacilli. This occurrence suggests the possibility of leprosy being endemic among wild chimpanzees in West Africa, potentially posing a zoonotic risk.</p>},
  year = {2011},
  journal = {Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association},
  volume = {80},
  pages = {29-36},
  month = {2011 Feb},
  publisher = {Nihon Hansenbyō Gakkai},
  address = {Higashimurayama-shi },
  issn = {1342-3681},
  language = {jpn},
}