@article{2220, keywords = {Adult, Africa, Aged, Cohort Studies, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Incidence, Leprostatic Agents, leprosy, Male, Middle Aged, Recurrence, Risk Factors, Time Factors, Treatment Outcome}, author = {Gebre S and Saunderson P and Byass P}, title = {Relapses after fixed duration multiple drug therapy: the AMFES cohort.}, abstract = {
Relapse rates after multiple-drug therapy (MDT) have been low, although there remains a concern about the possibility of late relapse in those with an initially high bacterial load. In all, 502 patients in the AMFES cohort completed fixed-duration MDT and are included in this report. There have been no confirmed relapses in the AMFES cohort, in a follow-up period of up to 8 years after completion of treatment, even in the 57 cases with an initial average bacillary index of > or = 4.0, 20 of whom have been followed for more than 5 years after ceasing MDT. Methods of diagnosing a relapse are discussed.
}, year = {2000}, journal = {Leprosy review}, volume = {71}, pages = {325-31}, month = {2000 Sep}, issn = {0305-7518}, url = {http://leprev.ilsl.br/pdfs/2000/v71n3/pdf/v71n3a12.pdf}, doi = {10.5935/0305-7518.20000036}, language = {eng}, }