@article{22029,
  keywords = {Adult, Brazil, Cohort Studies, Female, Hematuria, Humans, Kidney Diseases, Kidney Function Tests, Leprosy, Multibacillary, Leprosy, Paucibacillary, Male, Middle Aged, Proteinuria, Risk Factors, Young Adult},
  author = {Daher E and Silva G and Cezar L and Lima R and Gurjão N and Mota R and Abreu KLS and Rocha N and Oliveira M and Libório A},
  title = {Renal dysfunction in leprosy: a historical cohort of 923 patients in Brazil.},
  abstract = {<p>We investigated the factors associated with renal dysfunction in leprosy patients from Brazil. We report on a historical cohort of leprosy patients followed in two hospitals in Fortaleza City in northeastern Brazil. The factors associated with renal dysfunction were investigated. A total of 923 patients were included, with a mean age of 41.5 ± 19.1 years, and 53.3% were male. Renal dysfunction was found in 35 cases (3.8%). Proteinuria was found in 4.8% of cases, haematuria in 6.8% and leukocyturia in 10.4%. Factors associated with renal dysfunction by multivariate analysis were: reaction episode (odds ratio [OR] = 3.9, P = 0.03), multibacillary classification (OR = 3.5, P = 0.02) and advanced age (OR = 1.04, P = 0.01). Four patients (0.4%) died. Leprosy is associated with renal dysfunction, especially in older patients and those presenting with reaction episode and multibacillary classification.</p>},
  year = {2011},
  journal = {Tropical doctor},
  volume = {41},
  pages = {148-50},
  month = {2011 Jul},
  issn = {1758-1133},
  url = {http://tdo.sagepub.com/content/41/3/148.full.pdf+html},
  doi = {10.1258/td.2011.100436},
  language = {eng},
}