@article{2080, keywords = {Adult, Erythema Nodosum, Humans, Iridocyclitis, Leprosy, lepromatous, Male}, author = {Daniel E and Ebenezer G J and ffytche T J and Sigamani A and Job C K}, title = {Epithelioid granuloma in the iris of a lepromatous leprosy patient; an unusual finding.}, abstract = {
This case report depicts a case of histopathologically confirmed polar lepromatous (LL) leprosy with a bacterial index of 4+. He experienced recurrent episodes of erythema nodosum leprosum (ENL) in the first 5 years after diagnosis. Skin smears became negative after 6 years of dapsone monotherapy and have remained negative since that time. At 23 years after diagnosis, the patient had developed cataracts and underwent intracapsular cataract extractions with broad-based iridectomies. In one of the iris specimens, histopathologic examination revealed a focal granuloma composed of epithelioid cells. Subsequently a lepromin skin test showed a positive Mitsuda reaction with a borderline tuberculoid histopathology. This clearly illustrates the immunological upgrading of a polar lepromatous patient, perceived first in the iris tissue.
}, year = {2000}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {68}, pages = {152-5}, month = {2000 Jun}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v68n2a05.pdf}, language = {eng}, }