@article{1981, keywords = {Anti-Bacterial Agents, Anti-Inflammatory Agents, Decompression, Surgical, Drug Therapy, Combination, Follow-Up Studies, Humans, Leprostatic Agents, leprosy, Leprosy, lepromatous, Neuritis, Prednisone, Severity of Illness Index, Treatment Outcome}, author = {Boucher P and Millan J and Parent M and Moulia-Pela J P}, title = {[Randomized controlled trial of medical and medico-surgical treatment of Hansen's neuritis].}, abstract = {
The aim of the study was to compare the results of the medical treatment alone and of the medico-surgical treatment on leprous neuritis. The patients were followed-up during 2 years, with regular neurological evaluations. The statistical study was performed using the Tukey test. Ninety-three nerves (ulnar, median, common peroneal and posterior tibial) with a deficit of less than 6 months duration have been studied in 31 leprosy patients. All the patients were treated by steroids but in some of them a nerve surgical decompression was performed. An improvement of the sensitive and motor deficit was observed in both groups. No significant statistical differences appeared between the 2 groups according to the nerve involved, the duration of the deficit, the form of leprosy and the type of antibacillary treatment. However, the medico-surgical treatment had a significant better result on pain and on major but incomplete nervous involvement. This study included a limited number of nerves, thus, it would be useful to perform others randomized assays to better define the indications of surgical decompression in the management of leprous neuritis.
}, year = {1999}, journal = {Acta leprologica}, volume = {11}, pages = {171-7}, month = {1999}, issn = {0001-5938}, language = {fre}, }