@article{1963,
  keywords = {Agammaglobulinemia, Antibody Formation, B-Lymphocytes, Cell Differentiation, Complement System Proteins, Humans, Hypergammaglobulinemia, Immunologic Deficiency Syndromes, leprosy, Lymph Nodes, Lymphocyte Depletion, Lymphoma, Parathyroid Glands, Phenotype, Plasma Cells, Receptors, Antigen, B-Cell, Syndrome, T-Lymphocytes, Thymus Gland},
  author = {Gajl-Peczalska K and Lim S D and Good R A},
  title = {B lymphocytes in primary and secondary deficiencies of humoral immunity.},
  abstract = {<p>The quantitative studies of B lymphocytes in peripheral blood have been performed in various forms of primary and secondary immunodeficiency disease in man. X-linked agammaglobulinemia was found to comprise two sub-types, one lacking B-cell population, the other showing low numbers of B lymphocytes. The absence of B cells in severe combined immunodeficiency was corrected by marrow transplants in 3 children. Cases of DiGeorge syndrome and lepromatous leprosy showed an absolute increase in numbers of B lymphocytes in peripheral blood, probably a compensatory mechanism in the market deficit of T-cell population and function. The reconstitution of DiGeorge syndrome by fetal thymus transplant reversed the abnormally high percentage of B lymphocytes.</p>},
  year = {1975},
  journal = {Birth defects original article series},
  volume = {11},
  pages = {33-5},
  month = {1975},
  issn = {0547-6844},
  language = {eng},
}