@article{1953,
  keywords = {Blood Cell Count, Complement System Proteins, Humans, Immune Adherence Reaction, leprosy, Lymphocytes, Receptors, Drug, T-Lymphocytes, Time Factors},
  author = {Sher R and Holm G and Kok S H and Koornhof H J and Glover A},
  title = {T and CR+ lymphocyte profile in leprosy and the effect of treatment.},
  abstract = {<p>Thymus-derived lymphocytes (T lymphocytes) and complement receptor-bearing lymphocytes (CR+ lymphocytes) were estimated by using erythrocyte rosettes and erythrocyte-antibody-complement rosettes as markers in untreated lepromatous and untreated tuberculoid patients and in healthy controls. Treated lepromatous cases were also investigated. Ten cases of untreated lepromatous patients were reassessed 6 months or more after therapy commenced. A significant decrease in both percentages and absolute numbers of CR+ cells in the untreated lepromatous leprosy subjects was observed. This decrease showed a return to normal levels after treatment. The percentage of T cells in the untreated lepromatous cases was normal; however, the absolute numbers of T cells and the total lymphocyte count showed a significant decrease. After therapy, the T cell population was unchanged but the total number of lymphocytes increased significantly with treatment. The absolute number of T and CR+ cells was significantly less in the untreated than in the treated lepromatous patients.</p>},
  year = {1976},
  journal = {Infection and immunity},
  volume = {13},
  pages = {31-5},
  month = {1976 Jan},
  issn = {0019-9567},
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420573/pdf/iai00217-0049.pdf},
  language = {eng},
}