@article{19464, keywords = {Antibodies, Bacterial, Antigens, Bacterial, Enzyme-Linked Immunosorbent Assay, Female, Humans, leprosy, Male, Mycobacterium leprae, Recombinant Proteins, Sensitivity and Specificity}, author = {Triccas J A and Roche P W and Britton W J}, title = {Specific serological diagnosis of leprosy with a recombinant Mycobacterium leprae protein purified from a rapidly growing mycobacterial host.}, abstract = {

In this report we demonstrate the utility of an monoclonal antibody inhibition enzyme-linked immunosorbent assay based on the Mycobacterium leprae 35-kDa protein, purified from the rapidly growing host Mycobacterium smegmatis, for the serodiagnosis of multibacillary leprosy. The assay proved highly specific (97.5%) and sensitive (90%) and compared favorably with two other established methods routinely utilized for leprosy serodiagnosis.

}, year = {1998}, journal = {Journal of clinical microbiology}, volume = {36}, pages = {2363-5}, month = {1998 Aug}, issn = {0095-1137}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105051/pdf/jm002363.pdf}, language = {eng}, }