@article{19119, keywords = {Adult, Biotransformation, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, Clofazimine, Humans, Leprostatic Agents, Liver, Male, Mass Spectrometry}, author = {Krishna D R and Mamidi R N and Hofmann U and Prabhakar C M}, title = {Characterization of clofazimine metabolites in humans by HPLC-electrospray mass spectrometry.}, abstract = {

Clofazimine (CAS 2030-63-9) is an important drug used in the treatment of leprosy. Its important metabolites are investigated by thin layer chromatography (TLC), HPLC (diode array) and HPLC-electrospray mass spectrometry. The resulting analytical data, extraction, isolation and characterization methods are presented. Their applicability is described for human urine analysis.

}, year = {1997}, journal = {Arzneimittel-Forschung}, volume = {47}, pages = {303-6}, month = {1997 Mar}, issn = {0004-4172}, language = {eng}, }