@article{1911, keywords = {Acute disease, Adolescent, Anti-Inflammatory Agents, Dapsone, Drug Hypersensitivity, Female, Hepatitis E, Humans, Leprostatic Agents, leprosy, Prednisolone, Syndrome}, author = {Chogle A and Nagral A and Soni A and Agale S and Jamadar Z}, title = {Dapsone hypersensitivity syndrome with coexisting acute hepatitis E.}, abstract = {
A 14-year-old girl presented with fever, generalized lymphadenopathy, skin rash and hepatitis after starting dapsone. All abnormalities reversed with institution of prednisolone therapy after discontinuation of dapsone. The hepatic involvement was of hepatocellular type; it was associated with IgM anti-HEV antibodies, suggesting coexisting acute hepatitis E. We believe a causal link between the hepatotrophic viruses and dapsone hypersensitivity syndrome could exist.
}, year = {2000}, journal = {Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology}, volume = {19}, pages = {85-6}, month = {2000 Apr-Jun}, issn = {0254-8860}, language = {eng}, }