@article{18652, keywords = {Biopsy, Coloring Agents, Double-Blind Method, Granuloma, Humans, leprosy, Leprosy, Borderline, Leprosy, lepromatous, Lymphocytes, Prospective Studies, Skin, Skin Diseases}, author = {Singh N and Bhatia A and Gupta K and Ramam M}, title = {Cytomorphology of leprosy across the Ridley-Jopling spectrum.}, abstract = {

OBJECTIVE: To evaluate the possible role of cytology in classifying leprosy lesions on the Ridley-Jopling scale.

STUDY DESIGN: A double-blind, prospective study comparing cytologic assessment of 30 clinically diagnosed cases of leprosy with their histopathology. May-Grünwald-Giemsa and Ziehl-Neelsen stain were done on slit skin smears and fine needle aspiration material.

RESULTS: Cytologic subclassification was possible in 23 cases as tuberculoid leprosy (11), midborderline (3), borderline lepromatous (5) and lepromatous leprosy (4). These correlated with histologic subtypes.

CONCLUSION: May-Grünwald-Giemsa complements Ziehl-Neelsen stain, yielding information almost comparable to that from histologic examination of skin biopsies.

}, year = {1996}, journal = {Acta cytologica}, volume = {40}, pages = {719-23}, month = {1996 Jul-Aug}, issn = {0001-5547}, doi = {10.1159/000333945}, language = {eng}, }