@article{18612, keywords = {Adult, Aged, Animals, Autoantibodies, BCG Vaccine, Carcinoma, Squamous Cell, Female, Humans, Immunoglobulin G, Immunoglobulin M, leprosy, Leprosy, lepromatous, Male, Middle Aged, Peripheral nerves}, author = {Desikan P and Parkash O and Narang P}, title = {Role of antineural antibodies in perpetuation of a pre-existing peripheral nerve damage in leprosy.}, abstract = {

This study was carried out in order to find out whether antineural antibodies had a role to play in perpetuating pre-existing nerve damage in leprosy. Indirect ELISA was carried out on sera from 20 leprosy patients and five normal controls using antigen prepared from peripheral nerves of a cured bacteriologically negative leprosy patient. None of the patients had significant levels of IgG antibodies whereas eight of them (40%) had significant levels of IgM antibodies. However, there was no correlation with duration of disease, treatment received, nerve enlargement or active neuritis. The nature of these antibodies is discussed.

}, year = {1995}, journal = {Indian journal of leprosy}, volume = {67}, pages = {293-300}, month = {1995 Jul-Sep}, issn = {0254-9395}, language = {eng}, }