@article{18543, keywords = {Adult, Biopsy, Capillaries, Erythema Nodosum, Glomerulonephritis, Humans, Kidney Glomerulus, leprosy, Male, Middle Aged}, author = {Date A and Thomas A and Mathai R and Johny K V}, title = {Glomerular pathology in leprosy. An electron microscopic study.}, abstract = {

Electron microscopic examination of renal biopsies from 19 patients with leprosy who had edema, proteinuria, or hematuria showed a proliferative glomerulonephritis in 12, amyloidosis in 2, and no lesion in 5. The proliferative glomerulonephritis was of different patterns: diffuse with or without exudation, focal, or mesangial. Subendothelial and/or subepithelial deposits were seen in five biopsies. Of the patients with glomerulonephritis, 3 had a reduced total serum complement level, 5 had erythema nodosum leprosum, 5 had evidence of recent streptococcal infection, and 2 had microfilariae in the peripheral blood. The significance of these findings is discussed.

}, year = {1977}, journal = {The American journal of tropical medicine and hygiene}, volume = {26}, pages = {266-72}, month = {1977 Mar}, issn = {0002-9637}, doi = {10.4269/ajtmh.1977.26.266}, language = {eng}, }