@article{18511, keywords = {Animals, Antibody-Dependent Cell Cytotoxicity, Antigen-Antibody Complex, Colony Count, Microbial, Immune Tolerance, Immunity, Cellular, In Vitro Techniques, Killer Cells, Natural, leprosy, Mice, Mycobacterium leprae, Time Factors}, author = {Vaishnavi C and Ganguly N K and Kaur S and Kumar B}, title = {Suppression of ADCC by immune complexes formed in vitro in Mycobacterium leprae-infected mice.}, abstract = {

Antibody-dependent cellular cytotoxicity (ADCC) was assessed in mice infected experimentally with Mycobacterium leprae and injected simultaneously with in vitro-formed immune complexes (IC). Significant decrease in the ADCC function was observed in animals given IC at zero day (0dIC) and 3 months (3mIC) post inoculation with M. leprae, when ADCC activity was assessed at 3, 6 and 9 months period. From the data obtained we believe that ADCC is suppressed by IC formed in vitro.

}, year = {1993}, journal = {Microbiology and immunology}, volume = {37}, pages = {49-53}, month = {1993}, issn = {0385-5600}, doi = {10.1111/j.1348-0421.1993.tb03178.x}, language = {eng}, }