@article{18357, keywords = {Adolescent, Adult, BCG Vaccine, Case-Control Studies, Female, Humans, leprosy, Malawi, Male, Odds Ratio}, author = {Baker D M and Nguyen-Van-Tam J S and Smith S J}, title = {Protective efficacy of BCG vaccine against leprosy in southern Malaŵi.}, abstract = {

This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malaŵi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.

}, year = {1993}, journal = {Epidemiology and infection}, volume = {111}, pages = {21-5}, month = {1993 Aug}, issn = {0950-2688}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2271193/pdf/epidinfect00040-0030.pdf}, doi = {10.1017/s0950268800056636}, language = {eng}, }