@article{18201, keywords = {Animals, Anti-Infective Agents, Antitubercular Agents, Colony Count, Microbial, Disease Models, Animal, Fluoroquinolones, leprosy, Mice, Mice, Nude, Microbial Sensitivity Tests, Mycobacterium leprae, Ofloxacin, Quinolones}, author = {McDermott-Lancaster R D and Banerjee D K}, title = {Activity of sparfloxacin against Mycobacterium leprae measured by the proportional bactericidal test.}, abstract = {
The activity of 25 mg/kg and 50 mg/kg sparfloxacin was measured against Mycobacterium leprae in normal (immunocompetent) mouse foot pads by the proportional bactericidal test. This was compared with the action of 25, 50, and 150 mg/kg ofloxacin by the same method. Sparfloxacin, at both concentrations, was found to be strongly bactericidal by this method, comparable to 150 mg/kg ofloxacin.
}, year = {1993}, journal = {International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association}, volume = {61}, pages = {605-8}, month = {1993 Dec}, issn = {0148-916X}, url = {http://ila.ilsl.br/pdfs/v61n4a12.pdf}, language = {eng}, }