@article{17781, keywords = {Adult, Antigens, Bacterial, Child, Disease Transmission, Infectious, Female, Glycolipids, Humans, leprosy, Male, Nepal, Serologic Tests}, author = {Soares D J and Failbus S and Chalise Y and Kathet B}, title = {The role of IgM antiphenolic glycolipid-1 antibodies in assessing household contacts of leprosy patients in a low endemic area.}, abstract = {

This study was carried out to assess the role PGL-1 antibodies may have to play in assisting with early diagnosis in close contacts of leprosy patients. Blood samples were collected from patients and contacts. It was found that 6.9% of index cases and 1% of healthy contacts were positive for PGL-1 antibody. None of the healthy contacts developed clinical leprosy and all had become seronegative at follow-up. We conclude that screening for PGL-1 antibodies has a limited role in the screening of healthy contacts and may not be of use in low endemic areas.

}, year = {1994}, journal = {Leprosy review}, volume = {65}, pages = {300-4}, month = {1994 Dec}, issn = {0305-7518}, url = {http://leprev.ilsl.br/pdfs/1994/v65n4/pdf/v65n4a03.pdf}, doi = {10.5935/0305-7518.19940031}, language = {eng}, }