@article{17673,
  keywords = {Antibodies, Bacterial, Humans, leprosy, Mycobacterium leprae, Sensitivity and Specificity, Serologic Tests},
  author = {Parkash O and Chaturvedi V and Girdhar B K and Sengupta U},
  title = {A study on performance of two serological assays for diagnosis of leprosy patients.},
  abstract = {<p>We compared 2 serological tests for the diagnosis of leprosy to test their performances. The tests include the serum antibody competition test (SACT) for the detection of antibodies to Mycobacterium leprae-specific epitope on 35 KDa protein molecule, and M. leprae gelatin particle agglutination assay (MLPA), for the detection of antiphenolic glycolipid-1 (PGL-1) antibodies. In both the assays a higher serological positivity was seen amongst multibacillary (MB) patients than those in paucibacillary (PB) patients. Taking all leprosy patients together, the sensitivity of SACT (59.7%) was observed to be statistically comparable to that of MLPA (66.9%). However, SACT proved to be more specific (97.7%) than MLPA (75.0%). The agreement between these 2 assays was observed to be moderate.</p>},
  year = {1995},
  journal = {Leprosy review},
  volume = {66},
  pages = {26-30},
  month = {1995 Mar},
  issn = {0305-7518},
  url = {http://leprev.ilsl.br/pdfs/1995/v66n1/pdf/v66n1a04.pdf},
  doi = {10.5935/0305-7518.19950004},
  language = {eng},
}